MONDAY, AUGUST 24

--"HOUSE"�(8:00-9:00 PM ET/PT) CC-HDTV 720p-Dolby Digital 5.1

PA: Viewer discretion is advised.

HOUSE AND THE TEAM WORK TO KEEP A HUSBAND AND WIFE ALIVE BUT ARE FORCED TO MAKE A DIFFICULT DECISION ON "HOUSE" MONDAY, AUGUST 24, ON FOX

Meat Loaf Guest-Stars

Charlotte, an older woman who has spent the last six months taking care of her husband Eddie (guest star Meat Loaf) while he's been dying of heart failure, is rushed to Princeton Plainsboro for immediate treatment after collapsing from respiratory failure at Eddie's deathbed. With Eddie still alive and taken to the hospital as well, the two of them become a double mystery when Eddie's condition sporadically improves in direct correlation to Charlotte's condition deteriorating. The urgency of Charlotte's medical condition breathes new life into their lacking romantic relationship, and their regrets of what could have been are replaced with genuine tenderness as Charlotte informs the team she wants Eddie to have her heart should she die before him. The team is forced to make a difficult choice as both of their lives are nearing an end in the "Simple Explanation" episode of HOUSE airing Monday, Aug. 24 (8:00-9:00 PM ET/PT) on FOX. (HOU-520) (TV-14 L)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase; Peter Jacobson as Dr. Chris Taub; Kal Penn as Dr. Lawrence Kutner; Olivia Wilde as Thirteen

Guest Cast: Meat Loaf Aday as Eddie; Colleen Camp as Charlotte; Mary Jo Deschanel as Julia; Ed Brigadier as Richard; Hart Boykin as Arthur; Bob Rusch as Phil; Debbie Campbell as Katherine; Taylor Hardwick as Rosabel; Liz Benoit as Nurse Anne; Bobbin Bergstrom as Nurse