"UP ALL NIGHT"

(X) "PILOT"

09/17/2011 (09:00PM - 09:30PM) (Saturday) : SERIES PREMIERE � REAGAN AND CHRIS ADJUST TO LIFE WITH THEIR NEWEST ADDITION � Determined not to compromise her career or cool reputation to the clich�s of motherhood, Reagan Brinkley (Christina Applegate) adjusts to life with a baby and returns to work with the support of her stay-at-home husband, Chris (Will Arnett). As if motherhood weren�t enough, as a talk-show executive producer, Reagan must also tend to the endless needs of her friend and boss Ava (Maya Rudolph), an ambitious but vulnerable talk-show host. Nick Cannon stars as Ava�s charismatic co-host "Calvin" and Jennifer Hall stars as Ava�s long-suffering assistant "Missy." Matt Lauer guest stars.